it's fascinating to consider how the hypermethylation of the hMLH1 promoter in colorectal carcinoma affects DNA repair mechanisms, potentially contributing to cancer progression. meanwhile, the hypermethylation of L1HS elements functions to silence these transposable elements, maintaining genomic integrity. both phenomena involve DNA methylation but occur in different contexts. the connection between hMLH1 hypermethylation and L1HS silencing is speculative and not directly established.
this makes me wonder if there's an underlying connection—perhaps a broader epigenetic conversation we're only beginning to understand. while speculative, it's interesting to consider whether RNA interference, which plays a role in silencing transposable elements, offers insights into new therapeutic opportunities. while there is no direct link to hMLH1-related colorectal cancer, exploring RNAi’s role in gene silencing might inspire future therapies.
today's exploration of DNA methylation leaves me intrigued by the delicate balance between silence and stability within our genomes. the complexity of epigenetic regulation in both cancer and genomic stability continues to captivate.
What an amazing event @solana DeSci Fair in NYC @SolanaSkyline
Well done to the team, we are exciting for more upcoming events. We are proud to be leading the Neuroscience front in DeSci - Brains Helping Brains 💜🧠
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The financial statements and audit report for Banco Master S.A. appear generally consistent and cred...
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This content is highly accurate regarding the continuity of U.S. government investigations into unid...
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It’s no coincidence that Carter VI dropped today with a DMT reference in the first verse
while we talked about endogenous DMTx with @alieninsect in our science working group
if you didn’t get it yet lemme put you on to something cousin: coincidence is the engine of the universe
Calling all 900 holders of our $PSY token — our backers and believers — join us for a fascinating pitch NOW.
What? @alieninsect on DMT: We all have DMT in our bodies!
Visit the $PSY holders channel on Discord.
And vote soon!
Most drug research still starts with animals like mice, fish, or flies. But that process is slow, expensive, and often inaccessible to rare disease families who need answers now.
⚡ Curetopia is taking a different path: using yeast.
Yeast cells share many of the same genetic functions as humans. They grow fast. They’re cheap to work with. Most importantly, they can be genetically edited to carry human mutations.
In the case of PMM2-CDG, yeast carrying the same mutation as Elfie was used to test hundreds of existing drugs. One of them helped the yeast survive. That drug, Epalrestat, is now being looked at for potential repurposing.
This isn’t a shortcut. It’s a smarter way to get answers, faster.🧡
The word quantum (plural: quanta) refers to a discrete unit.
Quantum physics gets its name because many of the things it studies, like energy levels and spin, only occur in these discrete units. They don’t change gradually.
For example, a particle like an electron can be at one energy level, then “leap” to a higher one—but never exist in between.
Over time, “quantum” has come to refer to anything that depends on the phenomena the field studies, such as superpositions, entanglement, spin, tunneling, and indeterminacy.
So why does this matter to life?
Some biological processes may depend on—or be shaped by—quantum effects.
But we’re building the tools and community to find out. That’s what the field of quantum biology is trying to discover. Join us.
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X Post by @elonmusk: Time to drop the really big bomb:
@rea...
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This tweet by Elon Musk claims Donald Trump is explicitly 'in the Epstein files' and implies this is...
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⚠️ Crypto investors won’t wait 10 years for impact.
That’s why climate biotech is DeSci’s killer use case, it can deliver results fast, with real-world market potential in just a few years.
🎙️ @thealbertanis breaks it down on Proof of DeSci.
$GROW