Val Pye

[Oliver Acton @OliverActon3]

Delighted to share that our manuscript describing the structural dynamics of SAMHD1 catalysis using time-resolved cryoEM and extensive biophysics is now available online. Fantastic collaboration between several labs and STPs @TheCrick https://t.co/0XPGBrXjpl

[Rebecca Thompson @Bex_16]

You can request a free SHINY, PURPLE and LIMITED EDITION pin from @thermofisher below, in celebration of women scientists in #ElectronMicroscopy for #InternationalWomensDay2024

Bonus points if you post a photo with your pin #EmpowerWomenInEM https://t.co/21q6FiHX2S

[Aravindan Ilangovan @ilango_aravind]

Still time to apply for this post doc position in our lab. Deadline 9th February.

[Val Pye @val_pye]

@Jacob_Lewis90 @MolHorizons Awesome news! Congratulations Jacob!!

[Val Pye @val_pye]

@TCR_Miller @ccs_ku_dk @UCPH_health @sarahruidiaz Happy birthday Tom!!

[Peak Proteins @PeakProteins]

'Building' up to the Holiday Season - Day 15.

Protein Structure Determination at Peak Proteins (part of Sygnature Discovery).

This structure is ATP synthase which catalyses the formation of the energy storage molecule adenosine triphosphate (ATP).

[Aravindan Ilangovan @ilango_aravind]

Excited to share our recent work on bacterial DNA replication initiation published in @NatureComms. Great collaborative effort with @heathmurraylab key contribution from @YardimciLab. Good team work overall @simopelliciari @Ch_Winterhalter Salome and Yumi
https://t.co/MZAV5e1wSA

[Peak Proteins @PeakProteins]

'Building' up to the Holiday Season - Day 6.

Protein Expression and Purification at Peak Proteins (part of @SygnatureDiscov ). At Peak Proteins we can express and purify proteins from E. coli, insect and mammalian cells.

https://t.co/7zXDup6uRD

[The Francis Crick Institute @TheCrick]

A Crick team including @ghostpathogen @MuraliMaradana @SaterialeLab and Gitta Stockinger have found that high levels of a molecule commonly found in cruciferous vegetables like broccoli could offer protection against the Cryptosporidium parasite 🥦🛡️🪱
https://t.co/HvWliTC8el

[Peak Proteins @PeakProteins]

'Building' up to the Holiday Season - Day 4.

At Peak Proteins we use the Fida 1 platform from @FIDATechnology for a number of our client projects.

📖Read more about how we use Fidabio
https://t.co/REuoub4CsF

[Peak Proteins @PeakProteins]

'Building' up to the Holiday Season - Day 2.

Day 2 - Horseshoe Crabs and Endotoxins!
At Peak Proteins (part of @SygnatureDiscov), we are experienced in minimising endotoxin levels where required by our clients for assays. Read to learn more !
https://t.co/TRohP4tOmF

[Peak Proteins @PeakProteins]

'Building' up to the Holiday Season - Day 1.

We're counting down to the holidays with a series of models highlighting what we do at Peak Proteins (part of @SygnatureDiscov ).
First up is our bioreactor @InforsUK - read more https://t.co/2Iffd5RdYk

[Peak Proteins @PeakProteins]

Agar Plate Art!
Recently Peak Proteins' scientists got creative and designed and produced bacterial art for entrance into the @ASMicrobiology 's “Microbiology in Space" Agar Art Contest.
🚀🦠🎨

https://t.co/xPM1lkJ5HY

[Emma Hesketh @HeskethEmma]

If you are interested in using #CryoEM and #Chemistry to study PROTACs for cancer treatment do a iCASE #PhD with James Hodgkinson, John Schwabe and me @LeicStructBio and @PeakProteins. Click here and scroll to the bottom ⬇️🔬https://t.co/71PualEHGt

[Jacob Lewis 🧬 📷 @Jacob_Lewis90]

Thrilled to share this review with @LMSpenkelink & @van_Oijen on the advancements in single-molecule approaches & cryo-EM🔬. These technologies are reshaping our understanding of DNA replication dynamics! #StructuralBiology #Biophysics #AcademicChatter https://t.co/BJiaC7NSmk

[McDonald Lab @ The Crick @LabMcDonald]

New from us! @TheCrick

Houghton, F.M., et al. Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly.

https://t.co/wCYaBqC6kz
https://t.co/DEgMzgQbcf

#CryoEM #CryoET #MX #Crystallography #StructuralBiology #Neurology #Glycotime #Science #SeeMyScience

[Costa Lab @CostaLabCrick]

Our study on the cover of Molecular Cell 🥳. Thanks @AgaGambus and @GS_Lab_Bham for a great collaboration.

Structure by Milos Cvetkovic❄️, @PaoloPassaretti🧬, Agata Butryn👩‍🔬.

Artwork by @petermindek and the https://t.co/M6Q6EjdoVc team.

[George Chiduza @ChiduzaGeorge]

Excited to share another paper from my time @TheCrick! Thanks to everyone involved, @e_almacellas @Stefano_De_Tito @val_pye @Alex_van_Vliet @sharontooze01. Looking forward presenting this work @LivUniISMIB next week. #autophagy #atg9 #atg2 #lipid #scramblase

[Val Pye @val_pye]

@SCWestLab @CharlesSwanton Congratulations Neil et al 🎉🎉🎉

[The West Lab @SCWestLab]

Our latest paper uses structural biology, biochemistry & biophysics to reveal the two-step catalytic mechanism of the human nucleotide pool sanitiser DNPH1. This will aid the development of novel inhibitors, which may be of use in breast cancer treatment. https://t.co/ktJJ8Enj9g