Naphak Modhiran

postdoc virologist @UQ : believes in imagination-💡 -traveller : loves nature 🏔🗻🏝🏖🛩📷

[Naphak Modhiran @cusycon]

Excited to share our recent work describing the broadly cross-reactive and protective flavivirus NS1 antibody in @DWatterson_ @ProfPaulYoung and Prof. George Gao and Yi Shi. 1/n https://t.co/MgtxG282oX

[Jacob @JacobMolBio]

AI for structural biology: given the right harness, tools, and compute, your preferred AI agent can tackle tasks such as building a protein structure from a cryo-EM density map.

In this case, Claude assembled a structure, compared its reconstruction to the published structure, then used ChimeraX to create these visuals and make this short presentation video.

[CEPI @CEPIvaccines]

🔉 CEPI is urgently accelerating the development of three investigational vaccine candidates towards clinical trials in response to the deeply concerning Bundibugyo ebolavirus epidemic.

More in the press release: https://t.co/9Me8RVv3CH

[Waggoner Lab @LabWaggoner]

Key human defenses against pathogens were forged billions of years ago in microbial battles with viruses @ScienceMagazine
https://t.co/33kgXThGnv

[World Health Organization (WHO) @WHO]

LIVE: Media briefing on #Ebola, #WHA79 and other global health issues with @DrTedros https://t.co/7XsBv6wjfe

[Sayed Abdel-whab (ORCID: 0000-0003-2103-0922) @Sayedabdelwhab]

As Ebola outbreaks continue, a broad pan-Ebola neutralizing antibody that boosts the breadth & potency of partner antibodies marks a promising step toward next-generation Ebola therapeutics.
https://t.co/gYZm8zdNGm
#npj_Viruses @SpringerNature @WHO

[Krutika Kuppalli, MD FIDSA @KrutikaKuppalli]

Great to see #DRC post the initial genomes from May 2026 Bundibugyo Virus Disease Outbreak.

It helps improve diagnostics, track transmission, and accelerate development of vaccines and therapeutics.

Transparent, real-time data sharing is essential for outbreak control.
https://t.co/ovQjvgFnv3

[Marion Koopmans, publications: https://pure.eur.nl @MarionKoopmans]

Impressive! Genome sequence of the virus causing the outbreak in DRC/Uganda shared. That will allow checking which types of assays can be used
https://t.co/SSEnfXHsDN?

[Prof. Dr. Benhur Lee, MD 🦠🧬🔬 @VirusWhisperer]

Useful and comprehensive review!

[Stella Liong @StellaLiong_]

Our new paper in @ScienceAdvances shows that TLR7, a viral RNA sensor, amplifies influenza-mediated vascular inflammation and dysfunction in pregnancy, leading to adverse maternal and foetal outcomes. https://t.co/g6zG2bDjxy

@Gemmagoesviral @noxbiology @OXIBgroup @RMIT_CRSH

[Le Cong@Stanford, AI+Bio+Gene-Editing @lecong]

Can we program cells like computers — using RNA?

Two years ago, our group trained the first language model to decode the regulatory grammar of 5′ UTRs in mRNA, published in Nature Machine Intelligence.

Today, we’re excited to share the next step, also in Nature Machine Intelligence:
“Programmable RNA translation through deep learning-driven IRES discovery and de novo generation.”
We built an AI engine to discover, predict, optimize, and generate IRES elements — RNA control modules that regulate translation initiation.

This brings us closer to programmable RNA systems that control when, where, and how strongly proteins are produced inside cells.

AI is no longer just helping us read biology.
It is beginning to help us write it and harness it.

The future of computing may not only run on silicon — it may also run inside living cells.
#AIForBiology #LLM #AI4S #AI #RNA #MachineLearning #Bioengineering

[UQ Chemistry and Molecular Biosciences @UQ_SCMB]

SCMB's Dr Rhys Parry explains why the Hantavirus is very different to COVID and why the ‘Andes virus’ won’t cause the next pandemic. Read more in his article in The Conversation - https://t.co/AVlAh3qPSR.

[World Health Organization (WHO) @WHO]

Update on #hantavirus:
As of 12 May, 12h00 CEST, a total of 11 cases, including 3 deaths, have been reported. Nine of the 11 cases are confirmed, and the other 2 are probable. All are among passengers or crew on the ship.

We expect more cases given the dynamics of spread on a ship and the virus’ incubation period.

At the moment, there is no sign that we are seeing the start of a larger outbreak.

Passengers and crew are being followed up in their countries, where WHO recommends a 42-day quarantine at home or in a facility starting from day of departure from the ship.

WHO Technical Note for the disembarkation & onward management of MV Hondius passengers & crew https://t.co/wl8ZnCYARZ

[Ben Brennan @bbrennan83]

📝 Conserved pathogenesis of ancestral & contemporary Oropouche virus in a murine pregnancy model (led by @tilstonlunel ) — out in Nature Comms 🦟 #Oropouche

https://t.co/QnlR5d10Mv

[gerdcastan @gerdcastan]

Hantavirus ANDV dashboard

https://t.co/8SHQ9mBRCk

[Mau @Mau10415616]

“Superpropagadores” y transmisión de persona a persona del virus andino en Argentina | New England Journal of Medicine https://t.co/yKq0VsKTr1

[Guenter GR @GrGuenter]

Sehr gutes Paper zur Aerosol Übertragung des ANDV Hantavirus von Mensch zu Mensch.

[Aurélien Sokal @AurelienSokal]

Excited to share the latest work of our team published in Cell @CellCellPress 🎉
Congratulations to the team and all the collaborators!
@NeckerInem @casanova_lab @institutpasteur @PChappert @GorochovG
Read the paper here 👇https://t.co/FSltAG2pMl

[Jeffrey S. Smith @JSmithMDPhD]

Excited to share a project using AlphaFold-guided design to identify functional nanobody binders to the itch receptor MRGPRX2! Excited about this and other computational approaches
Grateful to all especially leads @epharvey3 @katherine_susa https://t.co/dTTdr36vSn @NatureComms

[Benjy Renton @bhrenton]

You've probably been reading a lot about hantavirus, currently tied to an outbreak on the MV Hondius. Our team at the @pandemiccenter has an in-depth look into the cases so far in this week's Tracking Report.
https://t.co/Xtv1g6Ks7l

[Dr Richard Hirschson @richardhirschs1]

⚠️Hantavirus update.

So now there is an 8th case in Switzerland (ship passenger that disembarked early, not particularly unwell).
The French ‘case’ isn’t a real case, he is simply a contact for now who was on the flight to Johannesburg with the sick Dutch case (we will need to wait 8 weeks to see if he becomes symptomatic and tests positive).
Further cases are not unexpected though.
Current cases remains early generation H2H spread on ship.
We can expect a few second or third generation cases from flights or healthcare facilities where these patients are treated.

My previously reviewed article from @NEJM documents the person-to-person transmission dynamics in the Argentina outbreak:
34 cases, 11 deaths, four generations of human-to-human transmission.

This virus has very low pandemic risk, it’s too deadly and it’s R0 with isolation is far too low.

https://t.co/uVtr20FB3r