Top Tweets for #Tuftcells
📢We are excited to share our latest bioRxiv preprint from the Biton Lab!
We identify CD45 as a tuft cell–intrinsic negative regulator of intestinal type 2 immunity
We'd love to hear your thoughts and feedback!
🔗 https://t.co/Dq39rQriSl
#bioRxiv #MucosalImmunity #TuftCells
Let's talk about #TuftCells. 🗣️
Drs. Thornton Thompson & Jakob von Moltke explore #gastrointestinal tuft cell biology, including what their evolved functions are beyond helminth sensing, how they detect pathogens, and why tuft cells proliferate dramatically during type 2 responses. https://t.co/kabWPJ5NlJ
Intestinal #TuftCells can sense #helminths and regulate innate immunity, but there are still gaps in understanding how they are regulated or communicate with gut neurons, according to a new Science #Immunology Review. https://t.co/j1r2dgb1YF
A new Review delves into the functions of intestinal #TuftCells and pinpoints crucial knowledge gaps that remain, highlighting opportunities for future research. @jakob_moltke
Learn more in Science #Immunology: https://t.co/aJdD6IltTM
New research in mice published in Science #Immunology identifies the Spi-B–c-Kit–TSLP pathway in #TuftCells as a potential therapeutic target to reduce the severity of food #allergies and other type 2 inflammatory disorders. https://t.co/vuRZ8fpLM7
Day after Christmas blockbuster from @HCCvPDAC with @DelgiornoKathy, @NinaSteele17 @ballenpetersen and colleagues in @Dev_Cell.
1st author @Daniel_Salas671 (now in @lauradelongwood lab) scores a dynamite (TNT!).
Tuft cells are not found in the normal pancreas, how up in precursor lesions, and then mysteriously "disappear" in #PancreaticCancer. What gives?
With dual recombinase mice, the authors show that metaplastic tuft cells undergo tuft-to-neuroendocrine transition (TNT), resulting in formation of neural-like progenitor cells. These TNT-induced NRPs confer adverse prognostic impact on pancreatic cancer. @SearsRosie favorite molecule Myc makes an appearance as the diver of this TNT phenomenon in metaplastic tuft cells.
A new @Nature study from Lulu Huang, Dr. Jochem Bernink, Dr. @AmirGiladi, and a team in Dr. @HansClevers' lab explores how #TuftCells in the intestine regenerate after irradiation! ☢️
Check it out: https://t.co/5z70wIsDYf
Listen to the summary: https://t.co/wArKMQWGOZ
A new study in Science #Immunology describes how the epigenetic regulator #HDAC3 drives circadian changes in #TuftCells via TGFbeta signaling in mice. https://t.co/aYsqXnDYVQ
#TuftCells act as regenerative #stemCells in the human intestine, study finds @_Hubrecht @nature https://t.co/Hxy15cLZzx
Check out the latest release from Dr. @HansClevers' lab! 🧫
Lulu Huang, Drs. Jochem Bernink, @AmirGiladi, and their @_Hubrecht team reported #TuftCells as a damage-induced reserve intestinal stem cell pool in humans.
📖 Get the full story in @Nature.
https://t.co/YMyWni8mW9
Beautiful new cell biology study of everyone's favorite cell- tuft cells...#tuftcells
https://t.co/ZdvalV7PAY @KenLauLab Jennifer Silverman, Matthew Tyska
Dr. Eshleman @emeshlem discussing her exciting findings on #tuftcells at #ICMI2024 in Copenhagen. Looking forward to the the next @socmucimm meeting in 2026!
Fantastic new paper in @AGA_Gastro by @ARNesLab showing SOX4 is required for epithelial plasticity in PanIN, including our favorite #tuftcells. Must read!
New Paper! Jonathan Baldan, Juan Camacho and Marta Ballester from the lab find a genetic program driven by Sox4 promoting the resolution of tissue injury in pancreas regeneration and cancer. @JonathanBaldan @AGA_Gastro @UCPH_BRIC #tuft_cells #plasticity https://t.co/jRCkbx28h8
Wow, check out all about #tuftcells and #helminths and #AcetylCholine and about a 100 other things in this PACKED paper👇 https://t.co/dF1lnLtQmu
Happy #FluorescenceFriday! I never get tired of looking at #tuftcells (yellow).
#pathart #histoart #pathart #bioart #sciart #microscopy #intestine #colon
🔥Two elegant studies #Intestinal #TuftCells ‘#weep & #sweep’ response for intestinal #helminth clearance ‼️
🎯Independent of signaling to classical #immune cells, via direct effects on #epithelial cells & #worms 🔆@ImmunityCP@ImmunityCP 🆕
✅Tuft cell-derived #acetylcholine promotes epithelial #chloride secretion & intestinal helminth clearance👏
👉https://t.co/yaxbNAWEfM
✅Tuft cell acetylcholine is released into the #gut lumen to promote anti-helminth #immunity👏
👉https://t.co/vuQrOmmrfY
▶️Intestinal helminth clearance is delayed in mice lacking tuft cell #acetylcholine @NatRevImmunol🔥
https://t.co/NiwHPyAA5E
@AmerGastroAssn @my_ueg @ANMSociety @esnm_eu @GutBrainScience
#GITwitter #MedTwitter #ScienceTwitter
Happy #FluorescenceFriday! 🌈
Today we're appreciating the spectacular explosion of colour from @AmyEngevik's #Microscopy! 🔬 Can you spot the #TuftCells? ⤵️
Some pretty good frozen sectioning and staining to identify a few tuft cells in yellow.
#TuftTuesday #bioart #sciart #colon #microscopy #pathart #histoart #intestine
Interested in #tuftcells and #microbiota? Check out this talk by @emeshlem tomorrow at 8:15am @ImmunologyAAI! #AAI2024
Amazing talks on the last day of #ASIP2024! @RachelStubler wowed us all with #tuftcells in #inflammation and @TicerTaylor and @ScientistSarah_ kept everyone on time as moderators!! Good job everyone!!
In 2020, right before shutdown, we (with @haber_lab_hsph) set out to understand the function of the olfactory TRPM5+microvillous cells. Like their relatives, the #TuftCells, they line the airway lumen and detect allergens. But their morphology, receptors and function in directing olfactory responses are quite distinct. @SciImmunology @AlexanderPerni @EvelynAvilesF
https://t.co/yK39ad2b0D
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